NCT06371365

Adverse Events for Free Flap Surgery in Head and Neck Cancer

Prescription Pattern and Adverse Events of Postoperative Antithrombotic Regimes for Free Flap Surgery in Head and Neck Cancer

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 540 (actual)
• Sponsor: Kaohsiung Medical University · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

This is a cohort study collecting patients with head and neck cancer who underwent free flap surgery at a single medical center between January 2019 and January 2022.

Detailed description

Patient information are collected from the electronic medical records retrospectively: Head and Neck cancer diagnosis: The International Classification of Diseases, Tenth Revision (ICD-10), which included C00-C14, C31, C32, C73, C75.0, C75.4 and C41.1. The cancer stage, alcohol use, betel nut, and smoking, and baseline comorbidities. Surgical characteristics including flap history, ablation time, reconstruction time, donor sites, recipient sites, neck dissection, flap size, anastomosis, artery types, vein types, intraoperative sealants used, and intravenous calcium channel blocker nicardipine to control hypertension after surgery.

Conditions

• Surgical Flaps
• Flap Failure Risk Factors
• Hematoma Risk Factors
• Thrombosis Risk Factors

Interventions

Type	Name	Description
PROCEDURE	Free Flap surgery	No intervention, this is an observational study

Timeline

• Start date: 2022-10-19
• Primary completion: 2023-09-24
• Completion: 2023-09-24
• First posted: 2024-04-17
• Last updated: 2024-04-18

Locations

1 site across 1 country: Taiwan