NCT06368843

the Impact of Ketamine Gargling on the Incidence of Post Intubation Sore Throat

Evaluating the Impact of Ketamine Gargling on Post Intubation Sore Throat: A Randomized Controlled Trial.

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 80 (estimated)
• Sponsor: Al-Azhar University · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Tracheal intubation often causes trauma to the airway mucosa, leading to postoperative sore throat (POST), which has been reported to occur in 21-65% of cases. While considered a minor complication, POST can contribute to postoperative discomfort and patient dissatisfaction.

Detailed description

Patients have ranked POST as the eighth most adverse effect during the postoperative period. Various methods, both non-pharmacological and pharmacological, have been explored to mitigate POST with varying degrees of success. Non-pharmacological approaches include using smaller-sized endotracheal tubes, lubricating the tube with water-soluble jelly, employing careful airway instrumentation, ensuring intubation after full relaxation, employing gentle oropharyngeal suctioning, minimizing intracuff pressure, and deflating the tracheal tube cuff completely before extubation, all of which have been reported to reduce the incidence of POST.

Conditions

• Postoperative Sore Throat

Interventions

Type	Name	Description
DRUG	Gargle with ketamine	The patients asked to gargling with ketamine solution in the preoperative waiting area after explain the whole procedure and the goals of the study.

Timeline

• Start date: 2024-04-25
• Primary completion: 2024-08-15
• Completion: 2024-09-20
• First posted: 2024-04-16
• Last updated: 2024-04-16

Locations

1 site across 1 country: Iraq

Regulatory

• FDA-regulated drug study