NCT06367036

Effect of Hypericum Perforatum Oil on Ecchymosis and Pain

Effect of Hypericum Perforatum Oil on Prevention Ecchymosis and Pain Associated With Subcutaneous Low Molecular Weight Heparin Injection: a Self-controlled Single-blind Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 160 (actual)
• Sponsor: Uskudar University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Low molecular weight heparin is a drug with anticoagulant and antithrombotic effects. This drug is frequently administered subcutaneously to patients by nurses. Complications such as pain, ecchymosis and hematoma may commonly occur at the injection site. This study investigated the effect of Hypericum Perforatum oil in preventing pain and ecchymosis after subcutaneous injection low molecular weight heparin. This quasi-experimental and single blinded study was conducted with 160 patients in a coronary intensive care unit. The researcher nurse applied 5-6 drops of Hypericum Perforatum oil to one arm of the patients 2 hours before the injection. The other arm of the patient was considered as the control arm. A total of 320 injections were administered. The evaluation of the injection sites was performed by two other researchers at 48th hours. The data were analyzed using Wilcoxon and McNemar test.

Conditions

• Pain
• Ecchymosis

Interventions

Type	Name	Description
OTHER	Topical hypericum perforatum oil intervention	The research nurse working in the CICU applied 5-6 drops of hypericum perforatum oil on one arm of the patient with a patting motion 2 hours before the injection. The area was left open for the oil to be absorbed. Only this nurse who administered the injection knows on which arm the oil was applied.

Timeline

• Start date: 2022-01-02
• Primary completion: 2022-12-29
• Completion: 2023-06-15
• First posted: 2024-04-16
• Last updated: 2024-04-16

Locations

1 site across 1 country: Turkey (Türkiye)