NCT06363214

Impact of Patient Blood Management (PBM) at the Schulthess Clinic

Impact of Patient Blood Management (PBM) at the Schulthess Clinic A Quality Assurance and Quality Control Project in Major Orthopaedic and Spine Surgery

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 16,000 (estimated)
• Sponsor: Schulthess Klinik · Academic / Other
• Sex: All
• Age: 16 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

Aim of this study is to analyze the transfusion requirements of allogenic blood products at the Schulthess Clinic for patients that had major orthopedic or major spine surgery between 2019 and 2024 order to identify patients at risk for transfusion. Moreover, impact of transfusion requirements and other measures of PBM on patient outcomes will be assessed. These data are required to further improve PBM at the Schulthess Clinic.

Detailed description

At the Schulthess Clinic a significant reduction of RBC's, fresh frozen plasma (FFP) and platelets transfusion could be observed between 2018 and 2022 during the stepwise introduction of PBM for all patients undergoing major orthopedic and spine surgery. RBC, FFP and PT transfusion declined by 76.3%, 73.5% and 99.2% over the 5-year period. Unfortunately however, at the moment no detailed analysis with respect to risk factors for transfusion, specific interventions or outcomes is available. The hypothesis is that the already known reduction of allogenic blood product transfusion at the Schulthess Clinic can be attributed to patients undergoing major primary joint arthroplasties, revision operations and major spine surgery. We assume that patient and procedure related risk factors over time did not significantly change while we expect a major impact of changed transfusion requirements and the stepwise PBM implementation on patient outcomes.

Conditions

• Patient Blood Management

Interventions

Type	Name	Description
PROCEDURE	Patient blood management	Perioperative optimization of hemoglobin level, perioperative minimization of blood loss, increase of anemia tolerance

Timeline

• Start date: 2024-05-01
• Primary completion: 2025-02-01
• Completion: 2025-04-01
• First posted: 2024-04-12
• Last updated: 2024-04-16