NCT06358131

Propofol Versus Midazolam in Sedation for Upper and Lower Gastrointestinal Endoscopy.

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 656 (estimated)
• Sponsor: Mansoura University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

There has been rapid growth in the number and complexity of gastrointestinal (GI) endoscopic procedures performed during the last decade. To ensure safe and effective upper GI endoscopy, the choice of an appropriate sedative agent is crucial. Sedation usually categorized into four stages: minimal, moderate, deep and general anesthesia. The upper gastrointestinal \[GI\] endoscopy usually performed under moderate sedation Sedation usually categorized into four stages: minimal, moderate, deep and general anesthesia. The upper gastrointestinal \[GI\] endoscopy usually performed under moderate sedation. Benzodiazepines still the most common sedative agents used for conscious sedation, either solely or in combination with opioids for upper GI endoscopy. Propofol is a hypnotic drug used for induction of anesthesia with short half-life that permits rapid patient recovery and discharge. Thus, its use is for upper GI endoscopy was adopted in many endoscopy centers. So we are going to Evaluate all adverse events related to anesthesia; in patients recruited for upper and lower endoscopy and compare between propofol and midazolam based anesthesia associated adverse events.Also we are going to Evaluate patient and endoscopist satisfaction as regarding propofol and midazolam anesthesia.

Conditions

• Gastrointestinal Diseases

Interventions

Type	Name	Description
DEVICE	Endoscopy	upper and lower endoscopy

Timeline

• Start date: 2022-01-01
• Primary completion: 2024-08-01
• Completion: 2024-08-01
• First posted: 2024-04-10
• Last updated: 2024-04-10

Locations

2 sites across 1 country: Egypt