NCT06355882

Patients With Low Cardiac Output Syndrome Undergoing Local Dental Anesthesia

Cardiovascular Events in Patients With Low Cardiac Output Undergoing Local Dental Anesthesia With and Without Epinephrine: Randomized, Double-blind Pilot Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 29 (estimated)
• Sponsor: University of Sao Paulo General Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Patients with low cardiac output syndrome requiring surgical and periodontal dental treatment will be selected to undergo the dental procedure using local dental anesthetic: 2% lidocaine with epinephrine and 2% lidocaine without vasoconstrictor. Cardiovascular events and the safety of using two cartridges (3.6 mL) will be evaluated. They will be evaluated by Holter monitoring in the period of 1 hour before, during and 1 hour after the procedure and blood pressure correction will be performed

Conditions

• Low Cardiac Output Syndrome

Interventions

Type	Name	Description
PROCEDURE	Anesthetic infiltration	Application of local dental anesthesia with two cartridges (3,6 mL) for dental procedures (tooth extraction or periodontal treatment) in patients with low cardiac output syndrome.

Timeline

• Start date: 2023-08-08
• Primary completion: 2024-12-01
• Completion: 2024-12-01
• First posted: 2024-04-10
• Last updated: 2024-04-22

Locations

1 site across 1 country: Brazil