NCT06355765

Citicoline & Antioxidants in Glaucoma

Effect of Oral Citicoline, Vitamins A, B, C and E, and Blackcurrant in Primary Open-Angle Glaucoma With OCT and Angiography

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 60 (actual)
• Sponsor: University of Naples · Academic / Other
• Sex: All
• Age: 30 Years – 90 Years
• Healthy volunteers: —

Summary

To evaluate the long-term effects of oral citicoline, vitamins A, B, C and E, and blackcurrant therapy in patients with primary open-angle glaucoma (POAG) using optical coherence tomography (OCT), OCT angiography (OCTA) and microperimetry parameters.

Detailed description

AIMS: To evaluate the long-term effects of oral citicoline, vitamins A, B, C and E, and blackcurrant therapy in patients with primary open-angle glaucoma (POAG) using optical coherence tomography (OCT), OCT angiography (OCTA) and microperimetry parameters. METHODS: Fifteen patients with POAG (treated group) received one soluble liquid sachet daily for 20 days a month of a complementary dietary supplement containing in fixed combination citicoline, vitamins A, B, C, and E, and blackcurrant for 1 year. Fifteen age-matched subjects affected by POAG were given a placebo and served as a control group. The patients underwent best corrected visual acuity (BCVA), Goldmann applanation tonometry, microperimetry examination, OCT, and OCTA at the beginning of the study and then at 1, 6 and 12 months.

Conditions

• Glaucoma, Open-Angle

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Citicoline blackcurrant supplement	Citicoline, Vitamins A, B, C and E, and Blackcurrant

Timeline

• Start date: 2022-01-10
• Primary completion: 2022-12-10
• Completion: 2022-12-10
• First posted: 2024-04-09
• Last updated: 2024-04-17

Locations

1 site across 1 country: Italy