NCT06354010

Cross-sectional and Prospective Study to Characterize Early-onset Presbycusis

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Sensorion · Industry
• Sex: All
• Age: 30 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to characterize and assess the evolution of hearing impairment of patients with adulthood-onset bilateral sensorineural hearing loss carrying mutations on GJB2 gene.

Detailed description

This study aims to characterize patients with adulthood-onset bilateral sensorineural hearing loss not due to any underlying medical condition (likely due to a genetic cause) and to assess the evolution of hearing impairment of those carrying mutations in GJB2 gene. Patients who present with adulthood-onset bilateral sensorineural hearing loss will be screened for the presence of mutation involved in hearing impairment. Patients with GJB2 mutations will be proposed to continue in a follow-up period.

Conditions

• Sensorineural Hearing Loss, Bilateral

Interventions

Type	Name	Description
GENETIC	Genotyping	Genotyping to determine if patients present mutations to the gene GJB2.
OTHER	Audiological assessments	Audiological assessments

Timeline

• Start date: 2024-06-14
• Primary completion: 2027-07-01
• Completion: 2027-07-01
• First posted: 2024-04-09
• Last updated: 2025-03-25

Locations

2 sites across 2 countries: United States, France