NCT06352606

Spinal and General Anesthesia in Neonates Undergoing Herniorrhaphy

Comparison Between Spinal and General Anesthesia in Neonates Undergoing Herniorrhaphy: A Randomized Controlled Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 74 (estimated)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 1 Day – 1 Month
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare spinal and general anesthesia in neonates undergoing herniorrhaphy.

Detailed description

Spinal anesthesia (SA) is a fast, simple and cost-effective method that has been used for the performance of inguinal hernias since the beginning of the 20th century in adults. One large observational study documented a low risk of post operative events with spinal anesthesia for inguinal hernia repair in infants . In addition, a randomized trial comparing reginal and general anesthesia in this population have not shown any significant differences in outcome. Spinal anesthesia reduces postoperative oxygen desaturation and respiratory morbidity when compared to general anesthesia (GA) in infants who underwent inguinal herniorrhaphy

Conditions

• Spinal Anesthesia
• General Anesthesia
• Neonates
• Inguinal Herniorrhaphy

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Spinal anesthesia	Oxygen supply will be done via nasal prong (2 L/min) when necessary. The local anesthetic used will be bupivacaine 0.6 mg/kg.
DIAGNOSTIC_TEST	General anesthesia	Patients will receive sevoflurane for induction and maintenance in an air/oxygen mixture along. Endotracheal tube will be inserted. No opioids or nitrous oxide was used intraoperatively.

Timeline

• Start date: 2024-04-06
• Primary completion: 2024-09-01
• Completion: 2024-09-01
• First posted: 2024-04-08
• Last updated: 2024-04-09

Locations

1 site across 1 country: Egypt