NCT06350656

Study of Cerebral Compliance in Neurosurgical Intensive Care Units (EC2)

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: Centre Hospitalier Universitaire de Saint Etienne · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Despite the massive use of intracranial pressure in neuro-resuscitation, there is still no cerebral compliance evaluation index used in current practice to guide therapy. In treatment guidelines for intracranial hypertension, patients are placed in a prone position at about 30 degrees. Several times a day, during nursing care, patients are flattened, which corresponds to a cerebral compliance test by adding a volume of cerebrospinal fluid to the cranial box.

Detailed description

This study aims to analyse the shape of the different components of the intracranial pressure waves (P1, P2, and P3) when the patient is flattened to determine an index to define the level of cerebral compliance.

Conditions

• Cerebrospinal; Disorder

Interventions

Type	Name	Description
OTHER	Clinical data collection	Post-retrieval from the medical record
OTHER	Therapeutic data collection	Post-retrieval from the medical record
OTHER	IntraCranial Pression (ICP) values collection	Post-retrieval of ICP values from the monitor

Timeline

• Start date: 2023-03-31
• Primary completion: 2024-04-01
• Completion: 2024-04-01
• First posted: 2024-04-05
• Last updated: 2024-04-05

Locations

7 sites across 1 country: France