Trials / Active Not Recruiting
Active Not RecruitingNCT06350422
Neuroimage Genome Study of Neuroplasticity Associated With Microgravity
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 26 (actual)
- Sponsor
- Chinese PLA General Hospital · Academic / Other
- Sex
- Male
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
This clinical trial investigates the neuroplasticity and cognitive status changes of the human brain in microgravity. To explore the relationship between cognitive status changes and brain functional activities, gray matter and white matter changes under microgravity exposure, screen and identify representative image markers, so as to provide decision-making information for the cognitive status changes of relevant personnel under microgravity environment.
Detailed description
MRI has the advantage of non-invasive and non-radiation, and imaging the human brain after exposure to microgravity can reveal the neuroplastic changes in the astronaut's brain and discover the characteristics of functional activities behind it. The purpose of this study is to explore the image features and cognitive state related information related to the changes of human brain neuroplasticity under microgravity environment, and to identify the related image markers. At the same time, the pathophysiological mechanism is preliminarily discussed in this study. This study is helpful for us to explore the sensitivity of different brain structures and brain functions to space microgravity environment, so as to further understand the role and influence of space missions on brain health.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Head-Down tilt Bed Rest test | All of the volunteers underwent 60 days of the Head-Down tilt Bed Rest test. |
Timeline
- Start date
- 2022-01-01
- Primary completion
- 2024-10-31
- Completion
- 2024-12-31
- First posted
- 2024-04-05
- Last updated
- 2024-04-05
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06350422. Inclusion in this directory is not an endorsement.