Trials / Recruiting
RecruitingNCT06349642
Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform
Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 324 (estimated)
- Sponsor
- Mayo Clinic · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This study is being done to collect tissue samples to test how accurately a tumor response platform, Elephas, can predict clinical response across multiple types of immunotherapies, chemoimmunotherapy and tumor types.
Conditions
- Early Stage Triple-Negative Breast Carcinoma
- Metastatic Bladder Urothelial Carcinoma
- Metastatic Cervical Carcinoma
- Metastatic Clear Cell Renal Cell Carcinoma
- Metastatic Colorectal Carcinoma
- Metastatic Endometrial Carcinoma
- Metastatic Esophageal Carcinoma
- Metastatic Liver Carcinoma
- Metastatic Lung Non-Small Cell Carcinoma
- Metastatic Malignant Skin Neoplasm
- Metastatic Malignant Solid Neoplasm
- Resectable Lung Non-Small Cell Carcinoma
- Early Stage Lung Non-Small Cell Carcinoma
- Resectable Malignant Solid Neoplasm
- Resectable Triple-Negative Breast Carcinoma
- Stage III Renal Cell Cancer AJCC v8
- Stage IV Cervical Cancer AJCC v8
- Stage IV Renal Cell Cancer AJCC v8
- Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
- Recurrent Cervical Carcinoma
- Recurrent Colorectal Carcinoma
- Recurrent Endometrial Carcinoma
- Recurrent Esophageal Carcinoma
- Recurrent Liver Carcinoma
- Recurrent Lung Non-Small Cell Carcinoma
- Recurrent Malignant Skin Neoplasm
- Recurrent Malignant Solid Neoplasm
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Biospecimen Collection | Undergo optional research blood sample. |
| PROCEDURE | Tissue Collection | Tissue specimen collection will be completed with your scheduled standard of care biopsy if possible. If standard of care biopsy is already completed or the research biopsy wasn\'t collected at the time as your standard of care biopsy, then the research biopsy will be scheduled for a different day for research purposes only. |
Timeline
- Start date
- 2024-04-24
- Primary completion
- 2027-05-01
- Completion
- 2027-05-01
- First posted
- 2024-04-05
- Last updated
- 2026-03-12
Locations
3 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT06349642. Inclusion in this directory is not an endorsement.