NCT06348290

Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects

a Single-center, Non-randomized, Open-label, Self-controlled Phase 1 Clinical Study to Evaluate Drug-drug Interactions of JMKX001899 Tablets in Healthy Subjects

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 72 (estimated)
• Sponsor: Jemincare · Industry
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This is an open-label, non-randomized, clinical study to evaluate the drug interaction between itraconazole, rifampin or Cocktail and JMKX001899 in healthy subjects. A total of three cohorts of 72 healthy subjects were planned to be enrolled in each cohort.

Conditions

• Solid Tumor, Adult

Interventions

Type	Name	Description
DRUG	JMKX001899	Oral
DRUG	Itraconazole	Oral
DRUG	Midazolam	Oral
DRUG	Rifampin	Oral
DRUG	dextromethorphan	Oral
DRUG	Rosuvastatin	Oral
DRUG	digoxin	Oral

Timeline

• Start date: 2024-04-01
• Primary completion: 2024-05-31
• Completion: 2024-09-15
• First posted: 2024-04-04
• Last updated: 2024-04-04