NCT06347965

Construction and Effect Evaluation of the Low Load Blood Flow Restriction Training Program for Lung Cancer Patients Complicated With Sarcopenia During Chemotherapy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 104 (actual)
• Sponsor: Xin Wang · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to verify the effectiveness and safety of the low load blood flow restriction training program. The intervention effect, tolerance and compliance of low load blood flow restriction training and progressive resistance training on lung cancer patients complicated with sarcopenia during chemotherapy will be compared, in order to provide new ideas for improving or reversing sarcopenia. The main questions it aims to answer are: Can low load blood flow restriction training improve sarcopenia in chemotherapy induced lung cancer patients? Which training method is more effective and tolerable between low load blood flow restriction training and progressive resistance training? Participants will be randomly divided into 3 groups： 1. Routine care group (Control group, CON): The researchers will provide participants with regular exercise and dietary guidance. 2. Low load blood flow restriction group (LL-BFRT): The researchers will provide participants with a low load blood flow restriction training program constructed by our research group. 3. Progressive resistance training group (PRE): The researchers will provide participants with progressive resistance training.

Conditions

• Sarcopenia
• Lung Neoplasms

Interventions

Type	Name	Description
BEHAVIORAL	Low load blood flow restriction training	Low load blood flow restriction training will be conducted on the subjects three times a week. Each training session includes upper and lower limb training, with 4 groups trained and repeated 30, 15, 15, and 15 times for each group. Train for a total of 12 weeks.The resistance strength will remain at 30% RM for weeks 1-12.
BEHAVIORAL	Progressive resistance training group	The subjects will undergo progressive resistance training three days a week, three groups per day, with each group repeating 10 times. Training includes upper and lower limbs. The resistance load increases over time, with a resistance load of 30% RM for weeks 1-4, 50% RM for weeks 5-8, and 70% RM for weeks 9-12.

Timeline

• Start date: 2023-02-01
• Primary completion: 2023-11-30
• Completion: 2024-02-20
• First posted: 2024-04-04
• Last updated: 2024-04-04

Locations

1 site across 1 country: China