NCT06347809

DNA Methylation in Adenocarcinoma of the Prostate: Analysis of Validated Biomarkers in Urine

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 24 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study explores the potential use of DNA markers in the detection of prostate cancer and patient perceptions of this screening approach and other current or future prostate cancer screening and diagnostic tests.

Detailed description

PRIMARY OBJECTIVE: I. To assess the accuracy of MDM candidates (individually and in combination) assayed from urine and prostatic fluid (collected following digital prostate massage) for detection of CAP. OUTLINE: This is an observational study. PHASE I: Participants undergo urine sample collection on study. PHASE II: Participants undergo standard prostate massage and collection of prostatic fluid and urine samples on study. All participants complete a questionnaire and have their medical records reviewed on study.

Conditions

• Prostate Adenocarcinoma
• Prostate Carcinoma

Interventions

Type	Name	Description
OTHER	Non-Interventional Study	Non-Interventional Study

Timeline

• Start date: 2019-01-23
• Primary completion: 2025-07-31
• Completion: 2025-07-31
• First posted: 2024-04-04
• Last updated: 2025-12-15

Locations

1 site across 1 country: United States