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UnknownNCT06347627

Communicating Human Papillomavirus Vaccine With Japanese Parents and Caregivers With Daughters Aged 12-18

Communicating Human Papillomavirus Vaccine With Japanese Parents and Caregivers With Daughters Aged 12-18: a Mixed-methods Assessment of Acceptance of HPV Vaccine With Experiments on Communication Strategies

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
1,600 (estimated)
Sponsor
The University of Hong Kong · Academic / Other
Sex
Female
Age
20 Years
Healthy volunteers
Accepted

Summary

This study aims to comprehensively assess confidence in and acceptance of human papillomavirus (HPV) vaccines among Japanese parents and caregivers with daughters aged 12-18 and their decision-making process.

Detailed description

This study will implement an experiment as a sixteen-arm randomized controlled trial in an online survey environment. Before the experiment, participants, who are Japanese caregivers with daughters aged 12-18 who have not received an HPV vaccine, will first answer a pre-experiment survey. The survey will collect information on participants' socio-demographic data and key decision-making factors for HPV vaccine acceptance and confidence. Then, the study will randomly assign the participants to view one digital communication message using a 2 × 2 × 2 × 2 between-person factorial experiment on 'components of message.' The sixteen experimental messages will be developed based on real social media messages posted between November 2021 and April 2022, when the Japanese government prepared to reinstate an active recommendation of HPV vaccines for eligible girls after eight and a half years of suspension. The sixteen messages will assess four factors: messenger, style, content, and misinformation. Each message will be similar except for one variable in consideration. The messenger component will be whether the message is from an individual or an organization. As individual messengers, the study will set a fictional male or female with common Japanese names who actively communicate about HPV vaccines. As organizational messengers, the study will use the existing accounts of the Ministry of Health, Labour and Welfare or the Japan Cancer Society or a fictional account of an anti-vaccine group. The style component will be whether the message conveys information through storytelling or scientific data. Messages will include personal stories for the storytelling style and statistics for the scientific data style. The content component will be whether the message conveys information about the effectiveness of the HPV vaccine in preventing diseases or the safety of the HPV vaccine. The contents will be built on both factual information and misconceptions about HPV vaccine safety and effectiveness that are often mentioned in the actual social media posts. The misinformation component will be whether the message conveys misinformation or factual information. The study will debrief all respondents exposed to misinformation after the survey. Lastly, the study will collect data as a post-experiment survey to evaluate how an online message influenced caregivers' trust, confidence, and motivation to vaccinate.

Conditions

Interventions

TypeNameDescription
BEHAVIORALGroup 1 (I x S x S x F)Experimental message: Individual x Safety x Storytelling x Factual
BEHAVIORALGroup 2 (O x S x S x F)Experimental message: Organization x Safety x Storytelling x Factual
BEHAVIORALGroup 3 (I x E x S x F)Experimental message: Individual x Effectiveness x Storytelling x Factual
BEHAVIORALGroup 4 (O x E x S x F)Experimental message: Organization x Effectiveness x Storytelling x Factual
BEHAVIORALGroup 5 (I x S x S x M)Experimental message: Individual x Safety x Storytelling x Misinformation
BEHAVIORALGroup 6 (O x S x S x M)Experimental message: Organization x Safety x Storytelling x Misinformation
BEHAVIORALGroup 7 (I x E x S x M)Experimental message: Individual x Effectiveness x Storytelling x Misinformation
BEHAVIORALGroup 8 (O x E x S x M)Experimental message: Organization x Effectiveness x Storytelling x Misinformation
BEHAVIORALGroup 9 (I x S x D x F)Experimental message: Individual x Safety x Scientific data x Factual
BEHAVIORALGroup 10 (O x S x D x F)Experimental message: Organization x Safety x Scientific data x Factual
BEHAVIORALGroup 11 (I x E x D x F)Experimental message: Individual x Effectiveness x Scientific data x Factual
BEHAVIORALGroup 12 (O x E x D x F)Experimental message: Organization x Effectiveness x Scientific data x Factual
BEHAVIORALGroup 13 (I x S x D x M)Experimental message: Individual x Safety x Scientific data x Misinformation
BEHAVIORALGroup 14 (O x S x D x M)Experimental message: Organization x Safety x Scientific data x Misinformation
BEHAVIORALGroup 15 (I x E x D x M)Experimental message: Individual x Effectiveness x Scientific data x Misinformation
BEHAVIORALGroup 16 (O x E x D x M)Experimental message: Organization x Effectiveness x Scientific data x Misinformation

Timeline

Start date
2023-12-22
Primary completion
2024-12-01
Completion
2024-12-01
First posted
2024-04-04
Last updated
2024-04-04

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT06347627. Inclusion in this directory is not an endorsement.