NCT06345261

Diphenhydramine in Catheter Related Bladder Discomfort

Role of Diphenhydramine in Prevention of Catheter Related Bladder Discomfort

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 104 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Diphenhydramine has H1-antihistamine action, it also possesses anti-muscarinic properties. Thus, diphenhydramine might be able to reduce the problem of catheter related bladder discomfort by inhibiting smooth muscle spasm of the urinary bladder via its anti-muscarinic action .

Conditions

• Catheter Complications

Interventions

Type	Name	Description
DRUG	DiphenhydrAMINE 50 Mg/mL Injectable Solution	injection of Diphenhydramine 50 Mg/mL
DRUG	Saline	injection of saline

Timeline

• Start date: 2024-04-01
• Primary completion: 2025-04-01
• Completion: 2025-05-01
• First posted: 2024-04-03
• Last updated: 2024-04-03

Locations

1 site across 1 country: Egypt