NCT06344338

Application of tDCS Stimulation in Controlling Refractory Status Epilepticus

Application of Targeting Transcranial Direct Current Stimulation (tDCS) Stimulation in the Treatment of Refractory Status Epilepticus

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (estimated)
• Sponsor: Xuanwu Hospital, Beijing · Academic / Other
• Sex: All
• Age: 14 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to assess the efficacy and safety of targeting tDCS stimulation for treatment of Refractory status epilepticus

Detailed description

After being informed about the study and potential risks, the recruited patients, giving written informed consent, will be determined of the eligibility for study entry. The patients who meet the eligibility requirements will be randomized in a 1:1 ratio to undergo targeting tDCS stimulation (up to 10 times) or sham stimulation.

Conditions

• Refractory Status Epilepticus

Interventions

Type	Name	Description
DEVICE	tDCS stimulation	In the real-stimulation group, Treatment was for 20 min, repeated twice in a day, then again over the next few days. The maximum number of stimuli required to terminate the status epilepticus should not exceed 10. In the sham-stimulation group, The duration and frequency of tDCS are the same as those in the treatment group, but the tDCS device is not active during the 20 minutes of sham-stimulation
DEVICE	TDCS sham-stimulation	TDCS sham-stimulation

Timeline

• Start date: 2024-04-01
• Primary completion: 2024-12-31
• Completion: 2025-03-31
• First posted: 2024-04-03
• Last updated: 2024-07-31

Locations

1 site across 1 country: China