Trials / Terminated
TerminatedNCT06341725
EUS Role in Non-metastatic Pancreatic Adenocarcinoma Lymph Nodes Staging
Role of Endoscopic Ultrasound to Assess the Lymph Nodes Staging in Non-metastatic Pancreatic Adenocarcinoma
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 2 (actual)
- Sponsor
- Paolo Giorgio Arcidiacono, MD · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
Aim of the study will be to investigate if Endoscopic Ultrasound (EUS) with elastography can be purposed between the routine staging examinations in patients with pancreatic adenocarcinoma without distant metastasis for the staging of lymph nodes status ("N" in TNM classification) * in RESECTABLE pancreatic cancer the investigators will evaluate the concordance with EUS elastography and histological findings of lymph nodes obtained during surgery, in order to assess the sensibility, specificity and the positive and negative predictive value of EUS with elastography, the disease-free survival, the percentage of metastatic patients and the overall survival (in patients with or without metastatic lymph nodes). * in "BORDERLINE resectable" and UNRESECTABLE non-metastatic ("advanced" locally") disease, the investigators will evaluate if the malignant lymph nodes samples during EUS with elastography and fine needle aspiration (FNA) will be related to a decreased survival. Secondary aim will be to register the prognosis (in terms of survival) of the patients with para-aortic and mediastinal pathological lymph nodes (related to a decreases survival in some series in literature)
Detailed description
Pathological lymph nodes will be assessed by EUS with elastography as lymph nodes: hypoechoic, rounded, rigid (blue) and big (bigger than 1 centimeter)
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | malignant lymph nodes | observational study |
Timeline
- Start date
- 2018-02-15
- Primary completion
- 2018-02-15
- Completion
- 2018-09-11
- First posted
- 2024-04-02
- Last updated
- 2024-04-02
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT06341725. Inclusion in this directory is not an endorsement.