NCT06341062

The Application of Contrast-enhanced Ultrasound in Acute Kidney Injury in ICU

The Application of Contrast-enhanced Ultrasound in Acute Kidney Injury in Intensive Care Unit

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 44 (estimated)
• Sponsor: Peking University Third Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to quantitatively assess renal microcirculation changes by contrast-enhanced ultrasound and to obtain systemic hemodynamic information by ultrasound Doppler at the same time, to analyze the relationship between renal microcirculation changes and systemic hemodynamic changes, and to explore its predictive value in renal function recovery in patients with critical acute kidney injury. The main questions it aims to answer are: 1. To explore the quantitative parameters of contrast-enhanced ultrasound which can reflect the changes of renal microcirculation. 2. To explore the relationship between renal microcirculation and systemic hemodynamics. 3. To explore the value of renal microflow changes quantitatively evaluated by contrast-enhanced ultrasound in predicting renal function recovery.

Detailed description

Quantitative analysis of cortical perfusion by contrast-enhanced ultrasound； Echocardiography； Quantitative results of renal artery and vein spectrum

Conditions

• Intensive Care Unit
• Acute Kidney Injury
• Ultrasound

Interventions

Type	Name	Description
OTHER	Renal microcirculation quantitatively assessed by Contrast-enhanced ultrasound	Renal microcirculation quantitatively assessed by Contrast-enhanced ultrasound before hospital discharge

Timeline

• Start date: 2024-04-15
• Primary completion: 2025-06-30
• Completion: 2026-06-30
• First posted: 2024-04-02
• Last updated: 2025-02-17

Locations

1 site across 1 country: China