NCT06339203

Wound Irrigation With Saline Versus Hypodilute-chlorhexidine After Cesarean Section (WISHES Study)

Wound Irrigation With Saline Versus Hypodilute-chlorhexidine After Cesarean Section: a Randomized Clinical Trial (WISHES Study)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 400 (estimated)
• Sponsor: Loma Linda University · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This investigator-initiated, open-label, randomized controlled trial will explore the effects of two treatment arms, comparing standard treatment with normal saline against Irrisept, a jet lavage solution containing a low concentration of Chlorhexidine Gluconate (CHG) at 0.05% in 99.95% sterile water for irrigation. The study aims to evaluate the impact on postoperative wound healing in patients who have undergone cesarean delivery.

Conditions

• Cesarean Section Complications
• Cesarean Section; Infection

Interventions

Type	Name	Description
DEVICE	Irrisept	450ml low concentration (0.05%) Chlorhexidine Gluconate (CHG) in 99.95% Sterile Water
DRUG	Normal Saline	450mL

Timeline

• Start date: 2024-06-05
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2024-04-01
• Last updated: 2025-06-05

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study