NCT06338397

Social & Affective Cognition in Alzheimer's Disease & Associated Disorders

Social & Affective Cognition as Determinant of Social Behavior in Alzheimer's Disease & Associated Disorders

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: University Hospital, Lille · Academic / Other
• Sex: All
• Age: 40 Years – 85 Years
• Healthy volunteers: Accepted

Summary

Recent studies have shown that individual neuropsychological scores of patients with Alzheimer's disease and Associated Disorders (ADAD) are only poorly correlated to their behavioral difficulties, such as disinhibition, apathy, social decision-making or vulnerability. Recently, social \& affective cognitive disorders have been highlighted as potential cause of social behavioral abnormalities. However, no previous studies have assessed the specific relationship between social \& affective cognition \& social behavior in ADAD. Our pilot study aims to explore the correlations between core and extended social \& affective cognitive processes and social behavior as observed during the neuropsychological examination, as well as to explore the common brain regions involved in those domains.

Conditions

• Alzheimer's Disease
• Frontotemporal Degeneration (Semantic & Behavioral Variants)

Interventions

Type	Name	Description
OTHER	SCANN	Administering 11 tests of social \& affective cognition to each participant as well as 6 scales to their study-partner, in order to have a detailed profile of social \& affective cognitive abilities that we can correlate to an 3DMRI with resting state procedure.

Timeline

• Start date: 2024-05-02
• Primary completion: 2027-05-02
• Completion: 2027-05-02
• First posted: 2024-03-29
• Last updated: 2024-03-29