Trials / Completed
CompletedNCT06337266
A Novel Online Calculator to Predict Long-term Survival and Recurrence Risk of Patients With Gastric Adenocarcinoma
A Novel Online Calculator to Predict Long-term Survival and Recurrence Risk of Patients With Gastric Adenocarcinoma After Radical Gastrectomy : A Multicenter Real-world Study
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 3,622 (actual)
- Sponsor
- Fujian Medical University · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
This study aimed to develop a novel Prognostic Oxidative Stress-Immune-Inflammatory Score (POSII Score) and introduce an innovative online calculator designed to predict long-term survival and assess the recurrence risk of gastric cancer (GC).
Detailed description
From 2009 to 2020, this study analyzed GC patients underwent Radical Gastrectomy at three hospitals, dividing them into training, internal, and external validation cohorts. Twelve blood indicators were analyzed. The POSII Score was developed in the training cohort using the Least Absolute Shrinkage and Selection Operator (LASSO) technique. Additionally, two online nomogram calculators were created based on multivariate Cox regression within the training cohort and subsequently validated in internal and external validation cohorts.
Conditions
Timeline
- Start date
- 2023-01-01
- Primary completion
- 2023-08-20
- Completion
- 2024-03-19
- First posted
- 2024-03-29
- Last updated
- 2024-03-29
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06337266. Inclusion in this directory is not an endorsement.