NCT06334926

BMI and Lymph Node Count in Colorectal Cancer

Prediction of Survival in Colorectal Cancer Patients on the Basis of Body Mass Index and Lymph Node Yield - a Retrospective Single Center Cohort Analysis Over a Quarter of a Century

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,192 (actual)
• Sponsor: Klinikum Floridsdorf · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Background and aim: Colorectal Cancer (CRC) is one of the most frequent cancer entities in the western world. It is known that obesity is one of the major risk factors for CRC. In contrast, mild obesity seems to have a positive effect on postoperative outcome, which is known as the "obesity paradox". Also, the number of resected lymph nodes (LN) during surgery is very important for correct staging. The aim of the present project is to evaluate the impact of BMI and LN-yield on long term overall survival (OS) of CRC patients treated with curative intent. Methods: Patients treated for CRC between 1998 and 2011 at the Klinik Favoriten in Vienna, Austria were analyzed in this retrospective single-center cohort analysis concerning OS.

Conditions

• The Aim of This Study is to Determine the Influence of BMI and Lymph Node Status on OS in CRC Patients in the Long Term

Interventions

Type	Name	Description
OTHER	no intervention, retrospective data analysis	not applicable, retrospective data analysis

Timeline

• Start date: 2017-12-01
• Primary completion: 2020-03-31
• Completion: 2020-03-31
• First posted: 2024-03-28
• Last updated: 2024-03-28

Locations

1 site across 1 country: Austria