NCT06334354

A Study of Changes in Thinking Related to Aging and Cancer in Breast Cancer Survivors (TRAC)

Cognitive Aging in Older Long-term Breast Cancer Survivors

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 420 (estimated)
• Sponsor: Memorial Sloan Kettering Cancer Center · Academic / Other
• Sex: Female
• Age: 60 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to look at how differences in cognitive (mental) function develop over time in breast cancer survivors compared to volunteers without a history of cancer (healthy volunteers). Both cancer survivors and healthy volunteers (who are the same age as the cancer survivors) will participate in this study so the researchers can compare the results of neurocognitive testing (which looks at memory, attention, and information processing) on each group of participants.

Conditions

• Breast Cancer Survivors

Interventions

Type	Name	Description
OTHER	Assessments	Sociodemographics, Deficit Accumulation Questionnaires, Remote Cognitive Assessment, Deficit Accumulation Questionnaires,Remote Cognitive Assessment
OTHER	Assessment (Survivors Only)	\*Tumor/Treatment Variables (Survivors Only)
OTHER	APOE and DNA Isolation	Biospecimens procurement and processing

Timeline

• Start date: 2024-05-10
• Primary completion: 2028-08-31
• Completion: 2028-08-31
• First posted: 2024-03-28
• Last updated: 2026-03-23

Locations

7 sites across 1 country: United States