NCT06331273

Impact of "No-touch" Technique on the Outcome of Liver Transplantation for Hepatocellular Carcinoma

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 800 (estimated)
• Sponsor: Zhejiang University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The "no-touch" technique has been one of the most important principles of oncological surgery and aimed to prevent seeding and tumor cell dissemination. Previous studies in hepatectomy have shown that no-touch technique surgery can reduce HCC recurrence and improve the survival of patients. However, there is no consensus on whether the no-touch technique in LT for HCC improves the outcomes. This study aims to prospectively include liver transplant patients from multiple transplant centers, collecting their pre-transplant clinical information, post-transplant pathological records and exploring and clarify the correlation between "no-touch" technique and the prognosis of LT patients.

Conditions

• Liver Transplantation
• No-touch Technique
• Hepatocellular Carcinoma

Interventions

Type	Name	Description
PROCEDURE	Liver transplantation with "No-touch" technique	The core principle of "no-touch" tumor surgery revolves around avoiding direct contact with the tumor or surrounding tissues as much as possible to minimize the release of cancer cells into the bloodstream or nearby tissues.

Timeline

• Start date: 2024-04-01
• Primary completion: 2028-04-01
• Completion: 2028-04-01
• First posted: 2024-03-26
• Last updated: 2024-03-26