NCT06329882

Doxycycline in Type II Diabetes

Doxycycline in Combination With Sitagliptin on the Glycemic and Cardiac Indices in Patients With Type 2 Diabetes Mellitus

• Status: Recruiting
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Mostafa Bahaa · Academic / Other
• Sex: All
• Age: 40 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease characterized by hyperglycemia, weight loss, and cardio-metabolic complications. T2DM develops due to the progression of insulin resistance (IR), impairment of insulin insensitivity, and failure of the pancreatic β-cells to release sufficient amount of insulin in response to glucose burden

Conditions

• Diabetes Mellitus, Type 2

Interventions

Type	Name	Description
DRUG	Sitagliptin 100mg	Sitagliptin is used along with diet and exercise and sometimes with other medications to lower blood sugar levels in adults with type 2 diabetes
DRUG	Doxycyclin	Doxycycline belongs to the class of medicines known as tetracycline antibiotics. It works by killing bacteria or preventing their growth.

Timeline

• Start date: 2024-03-30
• Primary completion: 2026-03-20
• Completion: 2026-04-20
• First posted: 2024-03-26
• Last updated: 2025-04-04

Locations

1 site across 1 country: Egypt