NCT06327165

Predictability of ANI (Analgesia Nociception Index) for Spinal Hypotension

Predictability of ANI (Analgesia Nociception Index) for Hypotension After Spinal Anesthesia in Patients Undergoing Cesarean Section

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 40 (estimated)
• Sponsor: Yonsei University · Academic / Other
• Sex: Female
• Age: 20 Years
• Healthy volunteers: Accepted

Summary

Spinal anesthesia is widely accepted as the anesthetic method of choice for Cesarean section. However, the incidence of spinal hypotension is 50-70%, and the decrease in blood pressure is often rapid and severe. Heart rate variability is influenced by various factors such as the sympathetic nervous system, parasympathetic nervous system, temperature regulation, baroreflex, and endocrine regulation, but high frequency heart rate variability above 0.15 Hz very specifically reflects the parasympathetic nervous system. The ANI monitor calculates heart rate variability mediated by changes in the parasympathetic nervous system. This study aims to determine whether ANI monitor can predict hypotension in patients undergoing a caesarean section under spinal anaesthesia while applying the preemptive vasopressor phenylephrine infusion protocol.

Conditions

• Cesarean Section
• Spinal Anesthesia

Interventions

Type	Name	Description
OTHER	observation	The ANI monitor calculates heart rate variability mediated by changes in the parasympathetic nervous system.

Timeline

• Start date: 2024-03-18
• Primary completion: 2024-12-31
• Completion: 2024-12-31
• First posted: 2024-03-25
• Last updated: 2024-03-27

Locations

1 site across 1 country: South Korea