NCT06325904

Uniportal VATS Versus Chest Tube for Early Empyema

Uniportal Video Assisted Thoracoscopic Surgery (VATS) Debridement Versus Chest Tube Drainage in Early Stage Empyema

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Minia University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This randomized controlled study compared uniportal video-assisted thoracoscopic surgery (U-VATS) versus chest tube drainage for initial (first-line) treatment of stage I (exudative) and stage II (fibrinopurulent) empyema in adult patients (\>18 years old). The primary end-point of outcome was the overall success of treatment (no need for re-intervention or death). The main results demonstrated the safety of minimally invasive U-VATS procedure in the initial treatment of early stages of pleural empyema in comparison to traditional chest tube drainage. Initial use of U-VATS was safe and feasible due to postoperative freedom from complex or marked effusion, in addition to significant reduction in the need for additional intervention, postoperative complications, length of hospital stay, and total cost.

Conditions

• Empyema, Pleural

Interventions

Type	Name	Description
PROCEDURE	Uniportal VATS	* single port video-assisted thoracoscopic surgery in the 5th intercostal space * performed under general anesthesia. * pleural fluid/pus was drained * pleural adhesions was removed
PROCEDURE	Tube thoracostomy	* Chest tube is inserted in 5th mid-axillary line * performed under local anaesthesia

Timeline

• Start date: 2021-03-01
• Primary completion: 2023-06-01
• Completion: 2023-12-01
• First posted: 2024-03-22
• Last updated: 2024-03-25

Locations

1 site across 1 country: Egypt