NCT06323603

Biomonitoring of Occupationally Populations Exposed to Micro and Nanoplastic

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 45 (estimated)
• Sponsor: Ricard Marcos · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The biomonitoring study aims to evaluate genotoxic damage and other parameters of exposure in different occupational exposed populations that work directly with different plastics.

Detailed description

The exponential increase in the production and use of plastic goods translates into a parallel increase of environmental plastic waste that is continuously degraded into micro and nanoplastics (MNPLs). Information on their effects on human health is still preliminary, especially regarding human biomonitoring studies, thus more information is required for risk assessment evaluation. This observational study aims to evaluate the exposure to MNPLs in human populations occupationally exposed to different types of plastics (fibers and plastic waste). The study will evaluate the effect of exposure to MNPLs (genotoxic and microbiota effects) in different body samples (blood, exfoliated buccal cells, urine,and feces) and also will use those samples to evaluate the presence of MNPLs.

Conditions

• Occupational Exposure
• Genotoxicity
• Damage Dna

Interventions

Type	Name	Description
OTHER	Micro and nanoplastic	Biological samples will be obtained to evaluate the different biomarkers selected

Timeline

• Start date: 2023-06-30
• Primary completion: 2024-06-01
• Completion: 2024-09-01
• First posted: 2024-03-21
• Last updated: 2024-03-25

Locations

4 sites across 2 countries: Finland, Spain