NCT06322875

A Clinical Study to Evaluate the Efficacy and Satisfaction of RHC Serum Combined With RHC(III) Injection

A Prospective, Single-center, Randomized, Split-face Controlled, Single-blind Evaluation, Superiority Clinical Trial to Evaluate the Efficacy and Safety of RHC(III) for Injection Combined With SkinCeuticals RHC Serum.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 54 (estimated)
• Sponsor: DeYi Aesthetic Medical Clinic · Academic / Other
• Sex: Female
• Age: 30 Years – 55 Years
• Healthy volunteers: Accepted

Summary

To evaluate the efficacy and safety of recombinant humanized collagen (type III) solution for injection combined with SkinCeuticals recombinant humanized collagen (RHC) serum Participants will be assessed by subjective questionnaire (FACE-Q Satisfaction with skin,Global Aesthetic Improvement Scale, et al) and some medical instruments (VISIA,Ultrascan UC22 et al)

Detailed description

With the growth of photoaging and age, more people have the appearance of fine lines, skin laxity, roughness. Clinical evidences shown that RHC III injection can effectively improve fine line, skin plumpness and firmness to some extent; SkinCeutials RHC serum is capable of improving skin plumpness, firmness and elasticity, and improve rough skin condition. A Prospective, single-center, randomized, split-face controlled, single-blind evaluation, superior efficacy clinical trial to evaluate the efficacy and safety of recombinant humanized collagen (type III) solution for injection combined with SkinCeuticals recombinant humanized collagen (RHC) serum, to explore the synergetic effects of injectable integrated skincare in Chinese population. A total of 54 subjects will be enrolled in this study, and half of the face of each subject will be randomly assigned 1:1 to the test side and the control side. The subjects will receive one injection of recombinant type III humanized collagen solution and will be followed up for 12 weeks after injection treatment. Experimental group: SkinCeuticals RHC cream and Regular cream (twice daily) Control group: Regular cream (twice daily) Participants will be assessed by subjective questionnaire (FACE-Q Satisfaction with skin,Global Aesthetic Improvement Scale, et al) and some medical instruments (VISIA,Ultrascan UC22 et al)

Conditions

• Facial Wrinkles

Interventions

Type	Name	Description
PROCEDURE	Recombinant type III humanized collagen solution for injection	Each subject will receive one injection of Recombinant type III humanized collagen solution for injection on the whole face
OTHER	SkinCeuticals recombinant humanized collagen (RHC) serum	Subjects received SkinCeuticals recombinant humanized collagen (RHC) serum application on the test side face
OTHER	Regular face cream smear	Subjects received Regular face cream smear application on the whole face

Timeline

• Start date: 2024-03-01
• Primary completion: 2024-07-01
• Completion: 2024-12-01
• First posted: 2024-03-21
• Last updated: 2024-03-21