NCT06321198

A Trial to Evaluate the Safety and Preliminary Efficacy of iMesenchymal Stromal Cells(iMSC) in Subjects With SR-aGVHD

A Trial to Evaluate the Safety and Preliminary Efficacy of Human Induced Pluripotent Stem Cell Derived Mesenchymal Stromal Cells in Subjects With Steroid-refractory Acute Graft-Versus-Host Disease

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (estimated)
• Sponsor: Anhui Provincial Hospital · Other Government
• Sex: All
• Age: 4 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

A study to evaluate the safety and preliminary efficacy of iMSC in subjects with SR-aGVHD

Detailed description

A multiple centers, open label, dose escalation study to evaluate the safety,tolerability and preliminary efficacy of iMSC in subjects with SR-aGVHD

Conditions

• Steroid-refractory Acute Graft-versus-host Disease(SR-aGVHD)

Interventions

Type	Name	Description
BIOLOGICAL	iMSC	Subjects will receive 4 or more times of iMSC injection

Timeline

• Start date: 2024-02-10
• Primary completion: 2027-03-02
• Completion: 2027-03-02
• First posted: 2024-03-20
• Last updated: 2026-03-27

Locations

1 site across 1 country: China