NCT06319261

Efficacy of Guided Biofilm Therapy (GBT) for Treatment of Deep Periodontal Pockets.

Efficacy of Guided Biofilm Therapy (GBT) for Treatment of Deep Periodontal Pockets: A Randomized Clinical Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: University of Baghdad · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

the aim of the study is to evaluate the efficacy of guided biofilm therapy (GBT) for treatment of deep periodontal pockets. the objectives are 1- To compare the change in the clinical periodontal parameters and microbiological parameters by using real time PCR for P. gingivalis, Aggregatibacter actinomycetemcomitans and Filifactor alocis among sites treated by GBT and conventional hand instrumentation after a period of 3 months and to assess the level of the selected periodontal pathogens in deep periodontal pockets and to estimate and compare deep periodontal pockets which need surgery after 3 months of non-surgical treatment by GBT and conventional hand instrumentation. the hypothesis is whether there are no differences in in the clinical and microbiological parameters among sites treated by GBT and conventional hand instrumentation after a period of 3 months or there are differences in in the clinical and microbiological parameters among sites treated by GBT and conventional hand instrumentation after a period of 3 months. The participants will be selected on a consecutive basis from patients referred to the Department of Periodontics, College of Dentistry, University of Baghdad. For each patient, each site will be randomly assigned to either treatment protocol: 1. Sites treated with GBT. 2. Sites treated with conventional manual instrumentation only.

Conditions

• Periodontitis

Interventions

Type	Name	Description
PROCEDURE	guided biofilm therapy	Removing plaque and calculus by initially detecting it with a disclosing agent followed by the use of air abrasive powder for the removal of supra and subgingival plaque.
PROCEDURE	root surface debridement	Removing plaque and calculus by conventional root surface debridement

Timeline

• Start date: 2024-04-01
• Primary completion: 2024-10-01
• Completion: 2024-12-01
• First posted: 2024-03-20
• Last updated: 2024-03-20