NCT06318858

Daily and Weekly Iron Supplementation in Infants

Efficacy of Daily and Weekly Iron Supplementation on Anemia Prevalence in Thai Infants Aged 6-12 Months

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 6 Months – 12 Months
• Healthy volunteers: Accepted

Summary

This study aims to compare the efficacy of daily iron supplementation and weekly iron supplementation in infants aged 6-12 months on the prevalence of anemia, hemoglobin level, and serum ferritin levels. Infants will be enrolled at 6 months and will be randomly assigned to receive either daily or weekly iron supplementation for the first 3 months and will be followed by weekly iron supplementation for another 3 months.

Detailed description

This study aims to compare the efficacy of daily iron supplementation and weekly iron supplementation in infants aged 6-12 months on the prevalence of anemia, hemoglobin level, and serum ferritin levels. Normal birth weight and term infants will be enrolled at 6 months based on the inclusion criteria. Eligible participants will be assessed at baseline, including anthropometry, dietary intake, and biochemistry (hemoglobin, iron status, vitamin A status, and inflammation). Participants will then be randomly assigned to receive either daily or weekly iron supplementation for the first 3 months. Participants will be followed up at 9 months for the same assessments and will receive weekly iron supplementation for another 3 months. Participants will be followed up at 12 months and the same assessments will be performed. After that, participants will go back to the routine health care service, weekly iron supplementation.

Conditions

• Anemia
• Iron Status
• Infants
• Iron

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Iron supplement	Group 1: 12.5 mg daily iron syrup supplementation from 6-9 months old

Timeline

• Start date: 2023-03-15
• Primary completion: 2024-08-14
• Completion: 2024-10-14
• First posted: 2024-03-19
• Last updated: 2024-04-05

Locations

1 site across 1 country: Thailand