NCT06318208

Pulmonary Function in Non-hospitalized Adults and Children After Mild COVID-19

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 110 (actual)
• Sponsor: University of Rostock · Academic / Other
• Sex: All
• Age: 6 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The study investigates whether patients with mild SARS-CoV-2 infection, who stayed at home during their infection and weren't hospitalized, have any persisting sequelae in pulmonary function. Therefore, 110 patients, aged 6-60 years, were recruited by telephone 4-12 weeks after laboratory-confirmed positive PCR and invited for a lung function testing. Every patient with abnormalities in pulmonary function was invited to a follow-up 3 months after the first appointment to assess changes in lung function values. Patients with a pre-existing lung disease and smokers within the last five years were excluded beforehand. Additionally to lung function testing we did a throat swab at each appointment to analyse via Multiplex PCR whether the patients had any other respiratory infection at the time of the pulmonary function testing.

Detailed description

110 patients, 90 adults and 20 children, were recruited. The lung function included LCI, FEV1, FVC and DLCO (Hb corrected). Additionally we did a throat swab at each appointment to analyse via Multiplex PCR whether the patients had any other respiratory infection at the time of the test.

Conditions

• SARS-CoV-2 Infection

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	lung function testing	lung function testing including LCI, FEV1, FVC, DLCO

Timeline

• Start date: 2021-04-20
• Primary completion: 2022-01-03
• Completion: 2022-01-03
• First posted: 2024-03-19
• Last updated: 2024-03-26

Locations

1 site across 1 country: Germany