Trials / Unknown
UnknownNCT06317818
Is Local Injection of Mesenchymal Stem Cells After Endoscopic Dilation Safe and Does it Improve the Outcome of Intestinal Stricture in Patients With Crohn's Disease?
- Status
- Unknown
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- Sponsor
- Centre Hospitalier Universitaire de Liege · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is an exploratory phase II study, to evaluate the impact of these Mesenchymal Stem Cells (MSCs) on strictures in Crohn's disease patients with symptomatic intestinal stricture eligible to endoscopic dilatation. The impact of combined treatment by endoscopic dilation and local injection of MSCs will be compared with that of a control group.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Mesenchymal Stem Cells | Suspension of mesenchymal stromal cells for intratissular injection |
| OTHER | Comparative placebo | Cell-free cell suspension solution devoid of cells for intratissular injection |
Timeline
- Start date
- 2023-06-06
- Primary completion
- 2025-08-01
- Completion
- 2025-08-01
- First posted
- 2024-03-19
- Last updated
- 2024-03-19
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT06317818. Inclusion in this directory is not an endorsement.