NCT06316921

Epidural PCA on Pain Relief After L-spine Surgery

Effect of Epidural Patient-controlled Analgesia on Postoperative Pain After Lumbar Spinal Surgeries

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 209 (actual)
• Sponsor: Taipei City Hospital · Other Government
• Sex: All
• Age: 60 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to evaluate the effect of epidural patient-controlled analgesia (PCA) on postoperative pain relief after lumbar spine surgeries. The eligible patients received two types of postoperative pain management: PCA and standard pain treatment. Comparisons between the two groups were made in terms of postoperative pain level.

Detailed description

This study included patients who underwent lumbar spine surgeries for degenerative spinal disease. The eligible patients were divided into two groups, the PCA group and the control group, for two types of postoperative pain management. The patients in the PCA group received 72-hour epidural PCA. The PCA catheter was inserted by the surgeon prior to wound closure in the lumbar spine surgery. The PCA catheter was maintained until 72 hours after the surgery and was removed at the postoperative day 4. The control group received postoperative standard pain treatment, including oral acetaminophen and muscle relaxants. No non-steroidal anti-inflammatory drugs were given in this study. All patients were provided the option to request intramuscular morphine injection (0.5 mg of morphine) for additional pain control, with a minimum interval of 6 hours between doses. Pain assessment was conducted using a visual analogue scale on the first four postoperative days and on the day of discharge. At the postoperative day 4, pain assessment was performed before the PCA removal. The level of pain and the number of morphine injections were compared between the two groups.

Conditions

• Pain, Postoperative
• Lumbar Spine Degeneration
• Analgesia, Patient-Controlled
• Epidural Anesthesia

Interventions

Type	Name	Description
PROCEDURE	Epidural patient-controlled analgesia	Epidural patient-controlled analgesia for postoperative pain after lumber spine surgery
PROCEDURE	Standard postoperative pain management	Standard of care for postoperative pain after lumber spine surgery

Timeline

• Start date: 2021-06-01
• Primary completion: 2021-12-31
• Completion: 2021-12-31
• First posted: 2024-03-19
• Last updated: 2024-03-19

Locations

1 site across 1 country: Taiwan