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RecruitingNCT06316791

Exploratory Clinical Study of CNCT19 Anti CD19 Cell Therapy in the Treatment of Refractory Autoimmune Diseases

Status
Recruiting
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
24 (estimated)
Sponsor
Juventas Cell Therapy Ltd. · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

Exploratory clinical study of CNCT19 anti CD19 cell therapy in the treatment of refractory autoimmune diseases,To evaluate the safety and tolerability of CNCT19 in patients with refractory systemic lupus erythematosus (lupus nephritis, immune thrombocytopenia), refractory ANCA-associated vasculitis, and refractory dermatomyositis on the basis of standard of care.

Conditions

Interventions

TypeNameDescription
BIOLOGICALsingle dose of CNCT19Autologous 2nd generation CD19-directed CAR-T cells, infusion intravenously.

Timeline

Start date
2021-12-14
Primary completion
2025-12-13
Completion
2025-12-13
First posted
2024-03-18
Last updated
2025-02-10

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT06316791. Inclusion in this directory is not an endorsement.

Exploratory Clinical Study of CNCT19 Anti CD19 Cell Therapy in the Treatment of Refractory Autoimmune Diseases (NCT06316791) · Clinical Trials Directory