NCT06315179

Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)

Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Seattle Children's Hospital · Academic / Other
• Sex: All
• Age: 6 Years – 21 Years
• Healthy volunteers: Not accepted

Summary

This is a prospective observational study collecting long-term clinical data and samples for research in pediatric inflammatory bowel disease (IBD) patients with gut inflammation and a control cohort of pediatric patients with disorders of the brain-gut interactions (DBGI) with no detectable gut inflammation.

Detailed description

Research procedures will coincide with clinical visits at institutional standards. As part of their clinical disease evaluation, participants will have blood, stool, and tissue collected as indicated by their disease course. Additional research samples or data will be collected during these visits. Participants will be asked to collect urine samples specifically for research.

Conditions

• Inflammatory Bowel Diseases
• Crohn Disease
• Ulcerative Colitis
• Indeterminate Colitis
• Functional Abdominal Pain Syndrome
• Functional Bowel Disorder
• Esophageal Diseases
• Gastroduodenal Disorder
• Bowel Dysfunction
• Gallbladder Diseases
• Sphincter of Oddi Dysfunction
• Anorectal Disorder

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Esophagogastroduodenoscopy (EGD) with biopsy	Esophagogastroduodenoscopy (EGD) is a test procedure to examine the lining of the esophagus, stomach, and first part of the small intestine.
DIAGNOSTIC_TEST	Colonoscopy w/ biopsy	Colonoscopy is a test procedure to examine the lining of the different portions of the large intestine: cecum, colon, rectum, and anal canal.

Timeline

• Start date: 2024-05-10
• Primary completion: 2028-01-01
• Completion: 2030-01-01
• First posted: 2024-03-18
• Last updated: 2025-05-15

Locations

1 site across 1 country: United States