NCT06314568

Radiochemotherapy and Interventional Radiotherapy in Vaginal Cancer

Radiochemotherapy Treatment Followed by Interventional Radiotherapy in Patients Affected by Vagina Carcinoma Multi-centric Prospective Observational Study Trimodal Definitive Invasive Vaginal Carcinoma Treatment

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 278 (estimated)
• Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Prospective observational multicenter study, aimed at evaluating the effectiveness on local control and cancer-specific survival of radiochemotherapy followed by interventional radiotherapy in patients affected by vaginal cancer

Detailed description

Prospective observational multicenter study, aimed at evaluating the effectiveness on local control and cancer-specific survival of radiochemotherapy (45Gy on pelvis and tumor plus chemotherapy with cisplatinum) followed by interventional radiotherapy (28Gy on residual tumor) in patients affected by vaginal cancer

Conditions

• Vaginal Cancer

Interventions

Type	Name	Description
RADIATION	Radiochemotherapy plus interventional radiotherapy	All patients with vaginal cancer will undergo radiochemotherapy (45 Gy on pelvis and tumor in association with cisplatinum) plus interventional radiotherapy (28 Gy on residual disease) with exclusive intent

Timeline

• Start date: 2024-03-15
• Primary completion: 2026-03-31
• Completion: 2028-12-31
• First posted: 2024-03-18
• Last updated: 2025-08-15

Locations

1 site across 1 country: Italy