NCT06313073

Neoadjuvant Radiotherapy for Breast Cancer

Neoadjuvant Radiotherapy Versus Adjuvant Radiotherapy for Breast Cancer: A Phase II Exploratory Randomized Controlled Clinical Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Changhai Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to compare the effects of neoadjuvant radiotherapy and adjuvant radiotherapy in patients with breast cancer. The main questions it aims to answer are: * The clinical effect of neoadjuvant radiotherapy for breast cancer was determined according to the postoperative specimens. * Evaluate the acute and late toxicity of preoperative radiotherapy Participants will be randomly divided into two groups: the neoadjuvant radiotherapy group and the adjuvant radiotherapy group.

Conditions

• Neoadjuvant Radiotherapy
• Breast Cancer

Interventions

Type	Name	Description
RADIATION	Neoadjuvant radiotherapy	The patient received synchronous radiotherapy and chemotherapy before surgery. CTV : 40Gy/15fx/3w, sequential GTV： 8.7-10Gy/3-4 Fx.CTV : 40Gy/15fx/3w, sequential GTV： 8.7-10Gy/3-4 Fx.
RADIATION	adjuvant radiotherapy	The patient received radiotherapy after surgery. CTV : 40Gy/15fx/3w, sequential GTV： 8.7-10Gy/3-4 Fx.CTV : 40Gy/15fx/3w, sequential GTV： 8.7-10Gy/3-4 Fx.

Timeline

• Start date: 2024-04-01
• Primary completion: 2026-02-15
• Completion: 2026-02-15
• First posted: 2024-03-15
• Last updated: 2024-03-15

Locations

1 site across 1 country: China