NCT06306170

Advanced Radiotherapy (ART) in Gynecological Cancer Patients (GYN-ART)

Efficacy of Advanced Radiotherapy (ART) in Gynecological Cancer Patients (GYN-ART)

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: IRCCS San Raffaele · Academic / Other
• Sex: Female
• Age: 18 Years – 90 Years
• Healthy volunteers: —

Summary

This is an observational mono-institutional study. Patients with gynecologic tumors treated with advanced radiotherapy- Image Guided Radiotherapy (IGRT), Intensity Modulated Radiotherapy (IMRT), Stereotactic Body Radiotherapy (SBRT)- will be included and toxicity and outcomes analyzed.

Detailed description

The patients with gynecological cancer treated with Advanced Radiotherapy (ART)- Image Guided Radiotherapy (IGRT), Intensity Modulated Radiotherapy (IMRT), Stereotactic Body Radiotherapy (SBRT)- at the Department of Radiotherapy of "IRCCS San Raffaele Scientific Institute" (IRCCSSRaffaele) from January 2005 to January 2024 will be identified and their clinical and dosimetric data retrieved and analyzed. The study objectives are the analysis of acute and late toxicity, and clinical outcomes, such as local, regional and distant control,disease free survival, cancer-specific survival, and overall survival. Secondary objective is the identification of prognostic factors for toxicity, disease progression, survival, including radiomic characteristics.

Conditions

• Gynecologic Cancer
• Radiotherapy Side Effect
• Radiotherapy; Complications
• Survivorship
• Progression, Disease
• Progression, Clinical

Interventions

Type	Name	Description
RADIATION	Image Guided Radiotherapy	Patients treated with IGRT, IMRT, SBRT for Gynecological cancer will be evaluated

Timeline

• Start date: 2024-02-15
• Primary completion: 2027-02-15
• Completion: 2029-02-15
• First posted: 2024-03-12
• Last updated: 2025-04-22

Locations

1 site across 1 country: Italy