NCT06301776

A Prospective, Experimental, Multicenter, Open-label, Randomized, Controlled Trial of 3-month Dual Antiplatelet Therapy Followed by Ticagrelor Versus 6-month Dual Antiplatelet Therapy Followed by Ticagrelor After Implanting Bridge

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 560 (estimated)
• Sponsor: The Fourth Affiliated Hospital of China Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

To compare the incidence of the composite endpoints of non-fatal ischaemic stroke, transient ischaemia (TIA) and all-cause mortality at 12-month follow-up after implantation of Bridge for the treatment of symptomatic vertebral artery stenosis in subjects who had been taking different durations of dual-antiplatelet therapy (3 vs 6 months) and ticagrelor monotherapy.

Conditions

• Brain Disease
• Vertebral Artery Stenosis

Interventions

Type	Name	Description
DRUG	Ticagrelor	To compare the safety and efficacy of different DAPT duration combined with ticagrelor monotherapy.

Timeline

• Start date: 2023-12-05
• Primary completion: 2025-12-31
• Completion: 2026-06-30
• First posted: 2024-03-08
• Last updated: 2024-03-08

Locations

1 site across 1 country: China