NCT06301178

Effect of Vitamin D Injection on Hypertrophic Scars and Keloids

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 35 (actual)
• Sponsor: Mostafa Bahaa · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Scars and keloids cause patients severe morbidity and psychological distress. Hypertrophic scars rise above the skin but stay within the scar boundaries, while keloids expand. The development of keloids and hypertrophic scars is a consequence of insufficient wound healing. These lesions are distinguished by excessive ECM deposition. Excessive ECM deposition is caused by increased inflammatory and proliferative processes and decreased remodeling activities. These scarring lesions are also linked to genetic and systemic causes

Conditions

• Dermatologic Disease

Interventions

Type	Name	Description
DRUG	Cholecalciferol	Vitamin D has various critical regulatory roles, including inflammatory control, cellular proliferation and differentiation, and wound healing regulation.

Timeline

• Start date: 2024-02-27
• Primary completion: 2025-02-20
• Completion: 2025-02-20
• First posted: 2024-03-08
• Last updated: 2025-04-08

Locations

1 site across 1 country: Egypt