NCT06298513

Autonomic and Metabolic Response to Cardiac Rehabilitation After Acute MI

Autonomic and Metabolic Response to Cardiac Rehabilitation After Acute Myocardial Infarction

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 25 (actual)
• Sponsor: Istituto Auxologico Italiano · Academic / Other
• Sex: Male
• Age: 25 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Ischemic heart disease remains the leading cause of death in the western world. The beneficial effects of cardiac rehabilitation on the evolution of ischemic heart disease are known, but the effects of rehabilitation on the metabolic processes of the patients are so far poorly understood. Metabolomics is the qualitative/quantitative analysis of the body's metabolic responses to pathophysiological stimuli or genetic alterations. Metabolic changes caused by physical activity have been demonstrated in obese and diabetic patients and in athletes. Aim of the study is to evaluate whether cardiac rehabilitation after a first myocardial infarction induces changes in the metabolic state of patients, and whether these changes may be related with changes in the usual risk factors (i.e. glyco-lipidic profile, natriuretic peptides, homocysteine).

Conditions

• Acute Myocardial Infarction: Rehabilitation Phase

Interventions

Type	Name	Description
OTHER	Cardiac rehabilitation	Six weeks of cardiac rehabilitation with physical training

Timeline

• Start date: 2023-05-02
• Primary completion: 2024-06-12
• Completion: 2025-01-13
• First posted: 2024-03-07
• Last updated: 2025-08-21

Locations

1 site across 1 country: Italy