NCT06294899

CRP and Lung Ultrasound in Respiratory Evaluation

Evaluation of Point-of-Care Ultrasound Along With C-Reactive Protein-Point of Care Tests Impact on Clinical Decision-making and Perceived Usefulness in Routine Healthcare Use in Patients With Lower Respiratory Tract Infection. Correlation Between C-Reactive Protein Concentrations and Lung Ultrasound Findings.

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 202 (estimated)
• Sponsor: Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Lower respiratory tract infections (LRTIs) are one of the most common reasons for consultation in Primary Care centres. Differentiating between viral and bacterial aetiologies can be challenging, leading to inappropriate antibiotic prescribing. Lung ultrasound (LUS), an imaging test that gained particular relevance since the beginning of the SARS-CoV-2 pandemic, offers several advantages over the classic chest X-ray in detecting and monitoring LRTIs, especially when pleural involvement exists. This study aims to correlate LUS findings with capillary blood C-Reactive Protein (CRP) values in patients with LRTIs, evaluating LUS as a diagnostic tool and its impact on therapeutic decisions. The descriptive observational study, conducted from January 2024 to December 2026 in Lleida, will include LRTI patients attending Primary Care centres. By validating LUS as a rapid and non-invasive diagnostic tool, unnecessary antibiotic prescriptions can be reduced, promoting LUS as a complementary test in Primary Care consultations. This will facilitate appropriate diagnosis and treatment decisions for patients with LRTIs, enhancing the overall management of respiratory infections.

Conditions

• Primary Health Care
• Lower Respiratory Tract Infection

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Lung ultrasound	Lung ultrasound will be performed to patients with suspected lower respiratory tract infections.
DIAGNOSTIC_TEST	C-Reactive Protein Test	C-Reactive Protein Test will be performed to patients with suspected lower respiratory tract infections.

Timeline

• Start date: 2024-06-01
• Primary completion: 2025-05-30
• Completion: 2028-09-01
• First posted: 2024-03-06
• Last updated: 2024-04-30