Trials / Completed
CompletedNCT06292988
Predictive Factors for Medullary Thyroid Cancer Aggressiveness
Predective Factors for Tumor Aggressiveness in Medullary Thyroid Cancer
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 500 (actual)
- Sponsor
- Aristotle University Of Thessaloniki · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This study is a retrospective study trying to find the predictive factors for medullary thyroid aggressiveness in terms of tumor metastasis and patients' survival.
Detailed description
This study is a retrospective study trying to find the predictive factors for medullary thyroid aggressiveness in terms of tumor metastasis and patients' survival. The predictive factors included in this study are central and lateral compartment lymph node metastases as well as distant metastasis up to 1 year postoperatively, while biochemical predictors (meaning ratios such as lymphocyte to monocyte ratio etc and CEA and calcitonin drop levels) and histological predictors (such as nuclear atypia, amyloid, immunohistochemistry, desmoplasia) are included as secondary outcomes. In this study , patients \>18 years old that underwent surgery for medullary thyroid cancer (total thyroidectomy, completion thyroidectomy) +/- central/lateral neck dissection) will be enrolled.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Total Thyroidectomy | Total thyroidectomy |
Timeline
- Start date
- 2024-03-01
- Primary completion
- 2024-04-15
- Completion
- 2024-04-15
- First posted
- 2024-03-05
- Last updated
- 2025-01-03
Locations
46 sites across 24 countries: United States, Austria, Belgium, Brazil, Bulgaria, China, Colombia, Croatia, France, Greece, India, Iraq, Italy, Jordan, Morocco, Poland, Serbia, Slovakia, Spain, Switzerland, Thailand, Turkey (Türkiye), Ukraine, Vietnam
Source: ClinicalTrials.gov record NCT06292988. Inclusion in this directory is not an endorsement.