NCT06286696

Optic Nerve Sheath Diameter in Hypertensive Emergency

Point-of-care Ultrasound of Optic Nerve Sheath Diameter in Suspected Hypertensive Emergency

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 375 (estimated)
• Sponsor: Leiden University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This prospective observational study investigates the potential of point-of-care ultrasonography of the optic nerve sheath diameter (ONSD) to rule out papilledema in patients with suspected hypertensive emergency. The primary focus is on assessing ONSD sensitivity in identifying papilledema (hypertensive retinopathy grade 4), while secondary endpoints include hypertensive retinopathy grade 3, hypertensive encephalopathy, and the need for intravenous rapid-acting medications to lower elevated blood pressure. This study aims to determine the diagnostic characteristics of this procedure for the diagnosis of hypertensive retinopathy, thus assessing its potential as a screening tool to rule out hypertensive retinopathy by the acute internal medicine doctor.

Conditions

• Hypertensive Emergency
• Papilledema
• Hypertension

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Optic Nerve Sheath Diameter	Point of care ultrasonography of the optic nerve sheath diameter

Timeline

• Start date: 2024-11-01
• Primary completion: 2026-11-01
• Completion: 2026-12-01
• First posted: 2024-02-29
• Last updated: 2024-10-09