NCT06285578

Effects of Probiotic and HIIT in Obese Women

Effects of Probiotic With HIIT on Cardiorespiratory Endurance and Metabolism in Middle-Aged Obese Women

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 47 (actual)
• Sponsor: University of Taipei · Academic / Other
• Sex: Female
• Age: 35 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to investigate whether there are the additive effects when implementing both high-intensity interval training (HIIT) and probiotics simultaneously on improving cardiorespiratory endurance and metabolism in middle-aged women.

Detailed description

High-intensity interval training (HIIT) is a time-efficiency exercise mode that has been shown to reduce body fat, fasting blood insulin levels, arterial stiffness, and aerobic capacity, helping to prevent and improve chronic diseases. Probiotics, on the other hand, have been found to have similar effects, including improving insulin sensitivity and endurance exercise performance, as well as reducing body fat. However, the additive effects of HIIT combined with probiotic supplements are unclear. In addition, on average, the life expectancy of women is longer than that of men. Middle-aged women are at high-risk for obesity and metabolic-related problems that threaten their long-term health. Therefore, whether the combination of HIIT and probiotics can be utilized to enhance the wellness of middle-aged women is the objective of this study.

Conditions

• Cardiorespiratory Fitness
• Metabolism
• Anthropometry

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Probiotics supplementation	Probiotics, Lactiplantibacillus plantarum TWK10, are packaged in powder form. Each participant consume one packet every day on a fasting status for 8 weeks.
BEHAVIORAL	HIIT training	HIIT training is conduct at the intensity of 85-90% VO2max for 2 minutes with 1-minute inactive resting interval, repeating for 7 times. 3 sessions per week for 8 weeks.
DIETARY_SUPPLEMENT	Placebo supplementation	Yeast powder replaces probiotics in each packet. Each participant consume one packet every day on a fasting status for 8 weeks.

Timeline

• Start date: 2018-10-01
• Primary completion: 2019-01-31
• Completion: 2019-03-01
• First posted: 2024-02-29
• Last updated: 2024-02-29

Locations

1 site across 1 country: Taiwan