NCT06284603

Effectiveness of Hyperbaric Oxygen Therapy in Adults

The Effects of Hyperbaric Oxygen Therapy on Physical Capacity, Health, and Gut Microbiota in Healthy Male Adults

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Poznan University of Physical Education · Academic / Other
• Sex: Male
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The goal of this controlled, experimental study is to learn about the effects of 10 sessions of hyperbaric oxygen therapy on physical performance, vascular circulation, biochemical parameters, and composition of the intestinal microbiota in young healthy men depending on the frequency of single treatments. The main questions it aims to answer are: 1. Do 10 treatments of hyperbaric oxygen therapy induce significant changes in physical performance levels, vascular circulation, and concentrations of biochemical parameters in young, healthy men? 2. Does the body's response to 10 treatments of hyperbaric oxygen therapy differ depending on the frequency of treatments? 3. Does a series of hyperbaric oxygen therapy treatments induce significant changes in the composition of the intestinal microbiota, metabolome, and functional status of the intestines? Participants are exposed to hyperoxia under hyperbaric conditions or form a control group with no treatment.

Conditions

• Healthy

Interventions

Type	Name	Description
DEVICE	Hyperbaric Oxygen Therapy - HBOT	Each session includes exposure of 60 minutes to 100% oxygen at 2.5 atmosphere absolute (ATA), with 5-minute air breaks every 20 minutes

Timeline

• Start date: 2022-03-01
• Primary completion: 2023-12-20
• Completion: 2023-12-20
• First posted: 2024-02-29
• Last updated: 2024-02-29

Locations

1 site across 1 country: Poland